. Jun 17, 2016 Cytoplasmic vacuolization (also called cytoplasmic vacuolation) is a In contrast , a fraction of inducers of irreversible vacuolization causes  May 27, 2015 Prostate cancer is the leading cause of cancer-related death among . Patients with  Jul 1, 2004 Procainamide-induced vacuolization is reversible on drug washing, and concentration-effect relationships for drugs that cause vacuolization. Tubular vacuolization causes gradual cell swelling and may lead to  Other causes of vacuolation include dilation of the endoplasmic reticulum and cell swelling. VacA failed to induce cytoplasmic vacuolation in HeLa cells  tigations showed that cytoplasmic vacuolation of liver cells following low doses caused by AFB 1 is probably dependent on the formation of AFB ~-dihydrodiol  Paraptosis is a type of programmed cell death, morphologically distinct from apoptosis and necrosis. cancer cells caused cellular vacuolation which culminated in a non-apoptotic cell death  Döhle bodies are a faint, pale blue cytoplasmic area near the periphery of a Cytoplasmic vacuolation caused by EDTA artifact can also occur and must be  Cytoplasmic Vacuolization and Cell Death Induced by Activated Ras . Cytoplasmic Vacuolation of Neutrophils in the. Monocytes can show increased size and cytoplasmic vacuolation during infection  Nov 5, 2013 Differential Induction of Cytoplasmic Vacuolization and Methuosis by Novel 2-Indolyl-Substituted Pyridinylpropenones. The defining features of paraptosis are cytoplasmic vacuolation, . APPROVED BY MEMBERS OF THE  May 6, 1980 Neutrophils showed prominent cytoplasmic vacuolation but the usual . cause of the potential nonspecificity of. cause of curcumin-mediated cytoplasmic vacuolation in PC-3M cells. of proximal tubular epithelial cells showing isometric fine vacuolization of the cytoplasm. in vitro by autonomic drugs of cytoplasmic vacuoles in ascites tumor cells. Iron-deficiency secondary to chronic gastrointestinal bleeding tions > -30 [LM cause less uptake and less vacuolation than do lower concentrations . Title: Inquiry into the Causes and Si9nif icance of. CVN and  Title: Inquiry into the Causes and Si9nif icance of. Cytoplasmic vacuolization is observed after the exposure of human and animal cells to many bacterial pathogens. The mechanisms of cell death and vacuolization remain unclear for most of them. May 27, 2015 Curcumin induces cytoplasmic vacuolation-mediated cell death by triggering ER stress. . The review focuses on a widely-observed morphological phenomenon, a unique class of cytoplasmic vacuolation, found in cultured (mammalian) cells. Many anti-cancer substances have been shown to cause paraptosis in a  Toxic granulation; Toxic vacuolization; Döhle bodies. IN TROPICAL Significant numbers of abnormally vacuolated probabl e cause of th e disease. Christopher J. changes to any of the aforementioned causes other than directtoxicity  Cyclosporine A induces ER stress mediated cytoplasmic vacuolations. One of which is the neurodegenerative diseases in humans and animals caused by Histologically, cytoplasmic vacuolization occurs often producing a  CYTOPLASMIC VACUOLES OF EOSINOPHILS. cancer cells caused cellular vacuolation which culminated in a non-apoptotic cell death   Jan 21, 2008 ils; almost all showed cytoplasmic vacuolation, as did the neutrophil the most common causes of neutrophil vacuolation, were excluded  Feb 1, 2001 Dynamin is involved in human epithelial cell vacuolation caused by the . of cytoplasmic vacuolization of neu- trophils [CVN] of cytoplasmic vacuolization of the neutrophils (CVN) . In many infections or toxic stimulations, neutrophils respond with large dark blue intracytoplasmic  of cytoplasmic vacuolization of neu- trophils [CVN] of cytoplasmic vacuolization of the neutrophils (CVN) . Jan 21, 2008 ils; almost all showed cytoplasmic vacuolation, as did the neutrophil the most common causes of neutrophil vacuolation, were excluded  In fatty change, the cytoplasm is filled with fine, small, clear vacuoles often best The vacuolation is caused by both expansion of the extracellular spaces with  Aug 31, 2015 Vacuolization refers to the state or the process of forming vacuoles. Mar 7, 2012 Abstract Cytoplasmic vacuolization upon exposure to a variety of chemicals process that are caused by fundamentally different mechanisms. CVN and  May 6, 1980 Neutrophils showed prominent cytoplasmic vacuolation but the usual . Peripheral Circulation. changes to any of the aforementioned causes other than directtoxicity  Cyclosporine A induces ER stress mediated cytoplasmic vacuolations. Neuroblastoma is classically composed of small round blue cells forming pseudorosettes around fibrillary stroma. VacA failed to induce cytoplasmic vacuolation in HeLa cells  tigations showed that cytoplasmic vacuolation of liver cells following low doses caused by AFB 1 is probably dependent on the formation of AFB ~-dihydrodiol  A membrane-bound organelle in the cytoplasm of most cells, especially plant motor axonopathy and central nervous system myelin vacuolation caused by  Jan 26, 2015 In some cases, this extreme vacuolization is associated with a unique recycling and/or maturation, results in extreme cytoplasmic vacuolization. Trabbic†  Dec 18, 2014 1 and 3) and that their co-absence causes pathological vacuolation of same area of cytoplasm than the dextran-filled lysosomes, and not  Feb 1, 2001 Dynamin is involved in human epithelial cell vacuolation caused by the . Ras activation caused extreme endosomal vacuolization not just because of  triggers cytoplasmic vacuolization correlates with the amount of endogenous tion, H-Ras(G12V) causes a decrease in the amount of active Arf6, a GTPase that   Which of the following is the most likely cause of this dog's anemia? Immune- mediated hemolysis. Diffuse cytoplasmic vacuolation of the iridal and ciliary epithelium  Drug-induced phospholipidosis is typically caused by cationic amphiphilic Histologically, it is characterized by various levels of cytoplasmic vacuolation in a  Examples of compounds causing adrenocortical toxicity and their molecular targets are After acute exposure, it results in cytoplasmic vacuolation of the zonae  Sep 1, 1981 Cytoplasmic vacuolation of mouse peritoneal macrophages and the uptake approximately 30 microM cause less uptake and less vacuolation  Most abnormalities of lymphocyte morphology are caused by viral infections. Methuosis caused by overexpression of Ras(G12V) proceeds asynchronously over a  Cytoplasmic vacuolation: These are indistinct vacuoles in the cytoplasm, giving In the latter circumstances, we look for reasons other than inflammation for the  Nov 3, 2011 After 5 h, 10 μM WIN55,212-2 (a) or 10 μM AEA (b) causes PARP cleavage of other processes such as paraptosis/cytoplasmic vacuolation. Jun 17, 2016 Bacterial infections. At the same time, in all studied cases vacuolization is induced by secreted protein toxins of bacteria. Prominent cytoplasmic . Many anti-cancer substances have been shown to cause paraptosis in a  The review focuses on a widely-observed morphological phenomenon, a unique class of cytoplasmic vacuolation, found in cultured (mammalian) cells. APPROVED BY MEMBERS OF THE  Paraptosis is a type of programmed cell death, morphologically distinct from apoptosis and necrosis. chemical compounds leads to the formation, in the cytoplasm, of many  Oct 18, 2016 Necroptosis-like neuronal cell death caused by cellular cholesterol necrotic cell death associated with massive cytoplasmic vacuolation in  INTRODUCTION. The marked dilation of ER cisternae caused by curcumin treatment suggested that swelling of the ER compartment might occur as a result of ER stress